AIPMT PRELIMS 2010 Zoology Respiratory System Multiple Correct Question
Which two of the following changes (a–d) usually tend to occur in the plain dwellers when they move to high altitudes (3,500 m or more)?
Increase in red blood cell size
Increase in red blood cell production
Increased breathing rate
Increase in thrombocyte count
Correct Answer
Detailed Explanation
When a person moves to higher altitudes the pO₂ and total atmospheric pressure decreases. Hypoxia stimulates the JG⁻cells of the kidneys to release erythropoietin hormone which stimulates erythropoiesis in bone marrow causing polycythemia. Hypoxia will also increase breathing rate. Initially, the size of RBCs will also increase, but will increase in number of RBC the size of RBCs becomes normal.
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