AIPMT PRELIMS 2010 Zoology Organ Transplantation Multiple Correct Question
Consider the following four statements (a–d) regarding kidney transplant and select the two correct ones out of these.
a. Even if a kidney transplant is proper the recipient may need to take immunosuppressants for a long time b. The cell-mediated immune response is responsible for the graft rejection c. The B⁻lymphocytes are responsible for rejection of the graft d. The acceptance or rejection of a kidney transplant depends on specific interferons
The two correct statements are
a & b
b & c
c & d
a & c
Correct Answer
Detailed Explanation
Kidney transplant is allograft. As no two individuals have the same HLA alleles or MHC proteins, except identical twins, the person requires immunosuppressant drugs like cyclosporin throughout his life. CMI, i.e., the T⁻cell mediated immunity is responsible for graft rejection.
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