STANDARD Zoology Enzyme Inhibition MCQ Question
Select the option which is not correct with respect to enzyme action.
Substrate binds with enzyme at its active site.
Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate.
A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate.
Malonate is a competitive inhibitor of succinic dehydrogenase.
Correct Answer
Detailed Explanation
The reduction of activity of succinate dehydrogenase by malonate is an example of competitive inhibition. Since a competitive inhibitor occupies the site only temporarily, the enzyme action is not permanently affected. Thus, addition of a lot of succinate can reverse the inhibition of succinate dehydrogenase by malonate.
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