STANDARDZoology-Endocrinology
STANDARD Zoology Insulin Structure MCQ Question
Type: MCQ-conceptual-Medium
C-peptide of human insulin is
A
A part of mature insulin molecule
B
Responsible for formation of disulphide bridges
C
Removed during maturation of proinsulin to insulin
D
Responsible for its biological activity
Correct Answer
Option C
Detailed Explanation
The insulin in mammals is synthesized from a preprohormone called preproinsulin. This prohormone is relatively inactive. Preproinsulin is the primary translation product of the insulin gene having 110 amino acids with a signal peptide and an extra stretch called the C peptide. Removal of C peptide converts proinsulin into insulin.
Found an issue with this question?