NEET 2026 Botany Sickle-cell Anaemia MCQ Question
Which one of the following disorders is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule?
Thalassemia
Sickle-cell anaemia
Phenylketonuria
Haemophilia
Correct Answer
Detailed Explanation
Sickle cell anaemia is an autosome linked recessive trait that can be transmitted from parents to offsprings when both partners are carrier for the gene. The defect is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at sixth position of beta globin chain of haemoglobin molecule.
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