NEET2026Botany-Genetic Disorders

NEET 2026 Botany Sickle-cell Anaemia MCQ Question

Type: MCQ-conceptual-Medium-Class 12

Which one of the following disorders is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule?

A

Thalassemia

B

Sickle-cell anaemia

C

Phenylketonuria

D

Haemophilia

Correct Answer

Option B

Detailed Explanation

Sickle cell anaemia is an autosome linked recessive trait that can be transmitted from parents to offsprings when both partners are carrier for the gene. The defect is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at sixth position of beta globin chain of haemoglobin molecule.

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