Botany-Mendel's Laws
NEET Botany Mendel's Laws Assertion Reason Question
Type: Assertion Reason-assertion-Medium-Class 12
Assertion (A): The substitution of valine for glutamic acid in the beta globin chain of haemoglobin leads to sickle cell anemia. | Reason (R): This substitution results from a single base change in the beta globin gene, causing polymerisation of haemoglobin under low oxygen tension.
A
Both A and R are true and R is the correct explanation of A.
B
Both A and R are true but R is not the correct explanation of A.
C
A is true but R is false.
D
A is false.
Correct Answer
Option A
Detailed Explanation
Both the assertion and reason are true. The substitution of valine for glutamic acid due to a single base change causes sickle cell anemia by leading to haemoglobin polymerisation under low oxygen tension.
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