AIPMT PRELIMS2008Chemistry-Organic Chemistry
AIPMT PRELIMS 2008 Chemistry Nucleophilic Substitution MCQ Question
Type: MCQ-conceptual-Medium-Class 11
The relative reactivities of acyl compounds towards nucleophilic substitution are in the order of -
A
acyl chloride > amide > ester > acyl anhydride
B
acyl chloride > ester > acyl anhydride > amide
C
acyl chloride > acyl anhydride > ester > amide
D
ester > acyl chloride > amide > acyl anhydride
Correct Answer
Option C
Detailed Explanation
Acyl chlorides are the most reactive due to the good leaving group Cl⁻, followed by acyl anhydrides, esters, and amides.
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