AIIMS 2018 Zoology Non-competitive Inhibition Assertion Reason Question
Assertion: Non competitive drugs alter the shape of active site of enzyme Reason: They attack on the active site of enzyme
If both assertion and reason are true and reason is the correct explanation of assertion.
If both assertion and reason are true but reason is not the correct explanation of assertion.
If assertion is true but reason is false.
If both assertion and reason are false.
Correct Answer
Detailed Explanation
Option C is correct because the assertion that non-competitive drugs alter the shape of the enzyme's active site is true; however, the reason provided is false. Non-competitive inhibitors bind to an allosteric site, not the active site, leading to a conformational change that reduces enzyme activity without directly blocking substrate binding. Option A is incorrect because the reason does not correctly explain the assertion. Option B is incorrect as it implies both statements are true and related, while option D is incorrect since the assertion is indeed true.
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