AIIMS 2018 Chemistry DNA Structure MCQ Question
Chargaff’s rule states that in an organism
Amount of adenine (A) is equal to that of guanine (G) and the amount of thymine (T) is equal to that of cytosine (C)
Amount of adenine (A) is equal to that of cytosine (C) and the amount of thymine (T) is equal to that of guanine (G)
Amount of adenine (A) is equal to that of thymine (T) and the amount of guanine (G) is equal to that of cytosine (C)
Amount of all bases are equal
Correct Answer
Detailed Explanation
Chargaff's rule states that in a double-stranded DNA molecule, the amount of adenine (A) is equal to that of thymine (T), and the amount of guanine (G) is equal to that of cytosine (C). This complementary base pairing is crucial for the structure of DNA, ensuring stability and accurate replication. Option A is incorrect because it incorrectly pairs adenine with guanine, while option B misstates the relationships between adenine, cytosine, thymine, and guanine. Option D is also incorrect as it suggests that all bases are present in equal amounts, which is not the case in most organisms.
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