AIIMS 2019 Botany Genetic Disorders Assertion Reason Question
Assertion: Phenylketonuria, Haemophilia and sickle cell anemia are genetic disorders
Reason: In phenylketonuria the person has a non-functional enzyme for the conversion of phenylalanine to tyrosine.
If both assertion and reason are true and reason is the correct explanation of assertion.
If both assertion and reason are true but reason is not the correct explanation of assertion.
If assertion is true but reason is false.
If both assertion and reason are false.
Correct Answer
Detailed Explanation
Option B is correct because it accurately identifies that while phenylketonuria (PKU) is a genetic disorder caused by a deficiency in the enzyme phenylalanine hydroxylase, haemophilia and sickle cell anemia are also genetic disorders but are not explained solely by the same mechanisms as PKU. Haemophilia is an X-linked recessive disorder affecting blood clotting, while sickle cell anemia is caused by a mutation in the HBB gene leading to abnormal hemoglobin (HbS). Other options are not applicable as they do not provide relevant information or context related to the assertion and reason statements. Understanding these distinctions is crucial in genetics, as it highlights the diverse nature of genetic abnormalities and their underlying mechanisms.
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