AIIMS 2017 Botany TCA Cycle Assertion Reason Question
Assertion (A) In TCA cycle isomerisation of citric acid into isocitric acid is done by change in CO₂ (C₀₀⁻) position.
Reason (R) Isocitric acid is more stable than citric Acid.
Both Assertion and Reason are true and Reason is the correct explanation of Assertion
Both Assertion and Reason are true but Reason is not the correct explanation of Assertion
Assertion is true but Reason is false
Both Assertion and Reason are false
Correct Answer
Detailed Explanation
Option D is correct because the assertion (A) is false; the isomerization of citric acid to isocitric acid involves the rearrangement of hydroxyl (–OH) and hydrogen (–H) groups rather than a change in the position of CO₂. Additionally, the reason (R) is also false; while isocitric acid is not necessarily more stable than citric acid, it is actually a transient intermediate in the TCA cycle. Options A and B are incorrect because they claim both statements are true, and option C is incorrect because it suggests that the assertion is true when it is not. Understanding the specific reactions and stability of intermediates in the TCA cycle is crucial for grasping metabolic pathways.
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